How Does CBD Bind With Cannabinoid Receptors?

CBD has little affinity for the two cannabinoid receptors. Instead, it acts as an indirect antagonist of cannabinoid agonists. This means that CBD may suppress the CB1 and CB2 activating qualities of other cannabinoids. CBD has also been found to interact with other non-cannabinoid receptors, including 5-HT1A and the vanilloid receptor TRPV-1. 

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